List of safety concerns per approved Risk Management Plan (RMP) of active substances per product (October 2023) (If you experience any difficulties to open the documents, please check the local security options in your local system/PC and/or within your browser (see also the browser option «open with») The update of the CMDh List of safety concerns per approved Risk Management Plan (RMP) of active substances per product is currently delayed. A new technical, database-driven solution is under development by CMDh.